Patient Knowhow - Medical Publications
Coronavirus
Sustainable social distancing through facemask use and testing during the Covid-19 pandemic
Medrxiv, April 6, 2020
Diego Chowell (MSKCC), Kimberlyn Roosa (Georgia State), Dr. Ranu Dhillon (Harvard), Gerard Chowell (Georgia State), and Patient Knowhow's founder, Devabhaktuni Srikrishna model the use of social protections such as masks to complement testing to control the Coronavirus pandemic which was referenced in an op-ed by Dr. David Kessler who led the Biden Coronavirus task force and also a StatNews article
A room, a bar and a classroom: how the coronavirus is spread through the air depends on heavily mask filtration efficiency
Medrxiv, November 13, 2020
Patient Knowhow's founder, Devabhaktuni Srikrishna models the use of masks in different indoor scenarios and explores how N95 masks (FFP2 in Europe) or masks with high-fit/filtration (hi-fi) could be significantly more effective at preventing the interhousehold spread of COVID-19
Ebola
Controlling Ebola: next steps
The Lancet, October 18, 2014
Dr. Ranu Dhillon (Harvard), Jeffery Sachs (Columbia), and Patient Knowhow's founder, Devabhaktuni Srikrishna, outline a strategy based on rapid diagnosis, patient isolation, and treatment to reduce the transmission to well under one additional person per infected case, thereby rapidly containing the epidemic to control the West African Ebola epidemic in 2014.
Ebola control: rapid diagnostic testing
The Lancet Infections Diseases, February 1, 2015
Gerardo Chowell (Georgia State), Dr. Ranu Dhillon (Harvard), and Robert Garry (Tulane), and Patient Knowhow's founder, Devabhaktuni Srikrishna, investigate the effect of reducing the time between symptom onset and diagnosis with rapid testing which can have a major reduction in Ebola transmission.
Overlooking the importance of immunoassays
The Lancet Infectious Diseases, October 1, 2016
Dr. Ranu Dhillon (Harvard), Dr. Dan Kelly (UCSF), Robert Garry (Tulane), and Patient Knowhow's founder, Devabhaktuni Srikrishna, discuss the importance of immunoassays as a diagnostic tool and which are overwhelmingly the front-line method for detecting HIV, Epstein-Barr, dengue, hepatitis C, influenza, and most other viruses
Deploying RDTs in the DRC Ebola outbreak
The Lancet, June 23, 2018
Dr. Ranu Dhillon (Harvard), Dr. Dan Kelly (UCSF), and Patient Knowhow's founder, Devabhaktuni Srikrishna, discuss the use or rapid diagnostic tests (RDTs) to uncover unknown Ebola transmission chains in the Democratic Republic of the Congo (DRC)
Getting to zero in the DR Congo Ebola outbreak
The Lancet Infectious Diseases, April 1, 2020
Dr. Ranu Dhillon (Harvard), Gerardo Chowell (Georgia State), and Patient Knowhow's founder, Devabhaktuni Srikrishna, use stochastic modeling to deteremine how if R is only brought marginally below 1, transmission could still linger for years whereas ending the outbreak might therefore require not just getting R below 1, but driving it down more aggressively to reach zero cases quickly.
Two data points for gauging outbreak control
The Lancet, December 8, 2018
Dr. Ranu Dhillon (Harvard) and Patient Knowhow's founder, Devabhaktuni Srikrishna, discuss two metrics, percentage of new cases from known transmission chains and symptom-to-isolation interval, which can provide greater clarity on how controlled an outbreak is.
When is contact tracing not enough to stop an outbreak?
The Lancet Infectious Diseases, December 1, 2018
Dr. Ranu Dhillon (Harvard) and Patient Knowhow's founder, Devabhaktuni Srikrishna, anticipatet the inabiilty of contact tracing to keep up with a fast moving novel pathogen as recently seen with Coronavirus.
Zika
Containing Zika while we wait for a vaccine
British Medical Journal, January 30, 2017
Dr. Ranu Dhillon (Harvard), Dr. Ashish Jha (Harvard), and Patient Knowhow's founder, Devabhaktuni Srikrishna discuss the use of rapid testing to control Zika's spread
Halting Zika’s resurgence with new rapid tests for the virus
British Medical Journal, May 31, 2017
Dr. Ranu Dhillon (Harvard), David Beier (Bay City Capital), and Patient Knowhow's founder, Devabhaktuni Srikrishna discuss the use of new diagnostic platforms as rapid tests for Zika
Lassa Fever
Early detection of Lassa fever: the need for point-of-care diagnostics
The Lancet Infectious Diseases, June 1, 2018
Dr. Ranu Dhillon (Harvard), Robert Garry (Tulane), and Patient Knowhow's founder, Devabhaktuni Srikrishna on use of rapid tests to control transmission in the Nigerian Lassa Fever epidemic.
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